Figure 2 | Scientific Reports

Figure 2

From: Actomyosin and vimentin cytoskeletal networks regulate nuclear shape, mechanics and chromatin organization

Figure 2

Cell spread area modulates nuclear state and mechanics. Plot shows results for nuclear height (a), volume (b), Poisson’s ratio (c), apparent elastic modulus (d) and chromatin condensation (e). Values for >50 cells were pooled to compute each individual data point. Data is presented as geometric mean, error bars indicate interquartile range (Q1–Q3). For the single case of Poisson’s ratio, data is presented as mean ± SD. For height data, the red line is the fit to the rational function defined as h = \(a+\frac{b}{c+CSA}\). Dotted lines indicate the values for average height of isolated nuclei and minimum nuclear height, as estimated using the fit.

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