Figure 3
From: A novel fluorescent probe-based flow cytometric assay for mineral-containing nanoparticles in serum
Uraemia is associated with the accumulation and ripening of CPP in patients with end-stage kidney disease. (a–c) Differences in (a) total CPP, (b) CPP-II and (c) SSC-H between control, PD and HD groups. (d) correlation of total CPP and CPP-II counts in all patients (n = 120). Line = median value. (e) Variability in the CPP-II/total CPP ratio between patient groups as for (a). (f) Lack of association between SSC-H and total CPP counts/μL in each group. (g) Between group differences in MBP and (h) the lack of association with total CPP counts. (i) Weak association of CPP-II and MBP counts. P-values for One-way ANOVA with Bonferroni correction or Kruskal-Wallis test with Dunns post-test for multiple comparisons (as appropriate) denoted as *P < 0.05, **P < 0.01, ***P < 0.001. For non-linear regression analyses (d,h,i), regression line (solid) with 95% confidence intervals (dashed) are shown. CNTRL, control; CPP, calciprotein particles; MBP, membrane-bound particles; HD, haemodialysis; PD, peritoneal dialysis.
