Table 2 Relationship of PSMA expression to clinicopathological parameters in well differentiated (primary papillary and follicular) thyroid carcinomas.

From: PSMA expression by microvasculature of thyroid tumors – Potential implications for PSMA theranostics

  

PSMA-positive

PSMA-negative

p-valuea

n = 72

n = 76

Age, mean ± SD (range), years

 

44.8 ± 18.1

47.6 ± 14.6

0.31

Sex

Male

17

15

0.55

 

Female

54

62

 

Tumor size, mean ± SD (range), mm

 

40.7 ± 24.7

31.3 ± 16.1

0.01

Positive surgical margin

 

14

8

0.16

Extrathyroidal extension

 

22

17

0.27

Capsular/vascular invasion*

 

24/32

30/42

0.79

PTC variant

Classic

29

20

0.07b

Follicular

12

21

 

Tall cell

4

1

 

Microcarcinoma

3

6

 

T category (1 + 2 vs. 3 + 4)

1

10

12

0.14

2

21

30

 

3

38

34

 

4

3

0

 

N category**

0

39

38

 

1

9

10

1.00

M category

0

69

74

 

1

3

2

0.67

Clinical stage (I + II vs. III + IV)

I

35

41

0.15

II

11

16

 

III

21

16

 

IV

5

3

 

MACIS score, mean ± SD (range)

 

5.4 ± 1.9

5.1 ± 1.4

0.23

  1. aTwo-tailed values based on t-test for continuous variables and Fisher’s exact test for categorical variables. bChi square test. *Only encapsulated tumors. **Only papillary cancers.
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