Figure 1 | Scientific Reports

Figure 1

From: Hyper-Stain Inspector: A Framework for Robust Registration and Localised Co-Expression Analysis of Multiple Whole-Slide Images of Serial Histology Sections

Figure 1

A screenshot of the Hyper-Stain Inspector software. The left panel contains the controls for various functions of the system, such as registration and IHC scoring. This panel also has a list box containing all of the whole slide images within the case, which the user can select or deselect to respectively load or unload the WSI into the system for viewing. Similarly to a slide viewer, loaded slides can be directly navigated to select a visual field for closer inspection. In addition, there are buttons which allow automated algorithms, such as registration and scoring, to be applied. The central and right panels show WSIs that have been loaded for viewing. Each panel contains a close-up viewing area (left), a view of the whole slide (top-right), and any auxiliary information about the slide (bottom-right). The slides shown have been registered and scored, the score is shown in the bottom-right, labelled as “Section score”, in addition, the area that was selected for scoring is highlighted on each image by a green line.

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