Figure 8 | Scientific Reports

Figure 8

From: Hyper-Stain Inspector: A Framework for Robust Registration and Localised Co-Expression Analysis of Multiple Whole-Slide Images of Serial Histology Sections

Figure 8

A demonstration of the nuclei cluster detection on two breast tissue slides. Despite many differences in the images, the extracted features are arranged very similarly and register the image well. A visual field from an ER stained slide is shown in Fig. 8a, with its nuclei cluster detection results shown in Fig. 8b. A visual field from an H&E stained slide is shown in Fig. 8c, with its nuclei cluster detection results shown in Fig. 8d. The registered visual fields are shown as a false colour image in Fig. 8e, with the ER image in blue and the H&E image in orange. The positions of the detected nuclei clusters following registration are shown in Fig. 8f, ER detections are shown in blue and H&E detections are shown in orange.

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