Table 6 Validation of MAB21L2, STXBP3 and RNF122 gene expression differences between pharmacologically-naive ADHD subjects and healthy unrelated controls by RT-qPCR.
Gene name | Gene Symbol | Gene ID | Location | Assay ID | Amplicon Size | ||
|---|---|---|---|---|---|---|---|
Assay information of target and control genes | |||||||
Housekeeping gene | |||||||
growth arrest and DNA damage inducible alpha | GADD45A | 1647 | 1p31.2 | Hs00169255_m1 | 123 | ||
Target genes | |||||||
mab-21-like 2 | MAB21L2 | 10586 | 4q31 | Hs00740710_s1 | 93 | ||
syntaxin binding protein 3 | STXBP3 | 6814 | 1p13.3 | HS01029364_m1 | 149 | ||
ring finger protein 122 | RNF122 | 79845 | 8p12 | Hs00227141 | 99 | ||
Target gene | Control gene | ODDS Ratio | Standard Error | Z-value | P-value | Number of controls | Number of cases |
Results from RT-qPCR validation of MAB21L2, STXBP3 and RNF122 genes | |||||||
RNF122 | GADD45A | 4.133 | 0.517 | 2.744 | 3.04e-03 | 34 | 42 |
STXBP3 | GADD45A | 2.361 | 0.521 | 1.648 | 0.049 | 40 | 44 |
MAB21L2 | GADD45A | 0.866 | 0.701 | −0.206 | 0.419 | 35 | 25 |
