Figure 4 | Scientific Reports

Figure 4

From: Escape from humoral immunity is associated with treatment failure in HIV-1-infected patients receiving long-term antiretroviral therapy

Figure 4

Molecular docking results showed the impact of adaptive mutations of HIV-1 Env on the binding ability of bnAbs. (a) VRC01 was colored in cyan in the docked VRC01 VH-VL binding to wild-type gp120 and colored in red in the docked VRC01 VH-VL binding to gp120 I371 V. (b) CH59 was colored in cyan in the docked CH59 VH-VL binding to wild-type gp120 V2 loop and colored in red in the docked CH59 VH-VL binding to gp120 V2 Q170K mutant. (c) 35O22 was colored in cyan in the docked 35O22 VH-VL binding to wild-type gp120 and colored in red in the docked 35O22 VH-VL binding to gp120 T240K mutant.

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