Table 1 Comparison of autonomic parameters in patients with and without orthostatic symptoms during head-up tilt test.

From: Patients with Orthostatic Intolerance: Relationship to Autonomic Function Tests results and Reproducibility of Symptoms on Tilt

Tests

Parameter

Total

OH

POTS

Normal HUT results

Without symptoms (n = 348)

With symptoms (n = 116)

Without symptoms (n = 94)

With symptoms (n = 38)

Without symptoms (n = 40)

With symptoms (n = 47)

Without symptoms (n = 214)

With symptoms (n = 31)

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

HUT

Baseline SBP (mmHg)

129.1

23.0

133.1

21.9

130.6

23.6

140.4

25.5

122.9

13.9

128.2

14.5

129.6

23.9

131.7

24.5

Baseline DBP (mmHg)

64.7*b

9.6

68.6*b

9.0

64.9

9.9

68.9

9.1

68.9

6.0

71.0

7.4

63.8

9.8

64.6

9.8

Baseline HR (bpm)

65.0

11.6

67.6

12.2

65.9

11.9

67.0

10.7

68.1

10.3

69.1

11.7

64.1

11.6

66.0

14.6

Decrease in maximum SBP (mmHg)

17.4*a

13.8

22.0*a

16.7

33.9

10.9

37.5

16.2

14.0

9.0

18.0

9.1

10.8

8.8

9.2

11.2

Decrease in maximum DBP (mmHg)

6.0

7.1

7.3

10.5

13.6

7.1

15.1

11.2

1.2

6.0

4.7

8.7

3.5

4.2

1.7

5.3

Increase in maximum HR (bpm)

17.3*c

10.6

26.1*c

14.0

14.2

7.6

17.0

10.7

39.5

7.1

39.4

8.5

14.5

6.7

16.9

5.9

VM

Fall of MBP in Phase IIE (mmHg)

11.6

8.0

11.2

7.5

14.0

9.6

14.7

8.7

10.7

8.8

9.9

5.6

10.7

6.9

11.5

8.4

Increase of MBP in Phase IIL (mmHg)

12.6*a

12.5

15.9*a

12.4

5.1

12.2

8.7

12.5

19.7

11.6

20.1

9.1

14.6

11.2

18.2

13.2

Difference in BP between the baseline and the end of phase II (mmHg)

0.8*a

14.5

4.7*a

13.6

8.9

16.8

4.0

15.5

8.0

9.7

10.2

8.1

3.8

11.9

6.6

12.9

Increase of MBP in Phase IV (mmHg)

13.6

12.9

14.7

13.3

7.9

12.4

8.2

10.6

21.6

13.8

18.8

13.5

14.6

11.9

16.2

13.4

PRT (second)

4.6

5.7

3.6

4.8

8.8

8.2

6.2

6.0

1.7

1.0

1.9

3.1

3.2

3.6

3.0

4.2

Total KOGS score

5.3*b

2.4

6.4*b

2.8

5.4

2.8

5.6

2.1

5.8

3.3

7.2

3.2

5.2*b

2.0

6.5*b

3.0

  1. SD = standard deviation; HUT = head-up tilt test; VM = Valsalva maneuver; HR = heart rate; SBP = systolic blood pressure; DBP = diastolic blood pressure; MBP = mean blood pressure; PRT = pressure recovery time; Phase IIE = early phase II; Phase IIL = late phase II; KOGS = Korean version of the orthostatic grading scale; OH = orthostatic hypotension; POTS = postural orthostatic tachycardia syndrome. *Significant between symptomatic and asymptomatic group (p < 0.05, total power > 80%); independent t-test. aSmall effect size in Cohen’s standard. bModerate effect size in Cohen’s standard. cLarge effect size in Cohen’s standard.
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