Figure 2

Correlation between the haplotype showing the highest efficiency thermogenesis and the latitudes (a) and mean annual temperatures (b) of global human populations deposited in the 1000 Genomes Project database. Blue line and grey band represent a regression line and its 95% confidence interval. Each color of triangle indicates the geographical region of populations. Dashed line represents a regression line, and orange triangle indicates the frequency and latitude of our subjects. The abbreviations used are the following: African (AFR): ESN (Esan in Nigeria), GWD (Gambian in Western Divisions in the Gambia), LWK (Luhya in Webuye, Kenya), MSL (Mende in Sierra Leone), YRI (Yoruba in Ibadan, Nigeria); European (EUR): FIN (Finnish in Finland), GBR (British in England and Scotland), IBS(Iberian Population in Spain), TSI (Toscani in Italia); East Asian (EAS): CDX (Chinese Dai in Xishuangbanna, China), CHB (Han Chinese in Bejing, China), JPT (Japanese in Tokyo, Japan), NJP (Japanese in this study), KHV (Kinh in Ho Chi Minh City, Vietnam); South Asian (SAS): BEB (Bengali from Bangladesh), PJL (Punjabi from Lahore, Pakistan).