Table 2 Top edge suggestions by models for ‘Gallstones’. The number of shown edges corresponds to the number of edges in the GHKG. For logistic regression, naive Bayes and noisy OR the edges are ranked by their relative importance score. For the GHKG, the edges are sorted according to two broad buckets symptom frequency that are provided in the graph [‘frequent’ and ‘always’]. The internal ordering of the edges within a given bucket is random. The stars associated with each edge represent the expected frequency for which “disease A causes symptom B” as rated by physicians. [‘***’ = ‘always happens’, ‘**’ = ‘sometimes happens’, ‘*’ = ‘rarely happens’, ‘’ = ‘never happens’].
From: Learning a Health Knowledge Graph from Electronic Medical Records
Top edge suggestions for ‘Gallstones’ | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Ranking (importance score) | Logistic regression Model | Naive Bayes Model | Noisy OR Model | Frequency (GHKG buckets) | GHKG | ||||
1 | Abdominal cramping from Gallstones | *** | Abdominal cramping from Gallstones | *** | Pain | *** | Frequent | Back pain | ** |
2 | Pain in upper-right abdomen | *** | Pain in upper-right abdomen | *** | Nausea | *** | Frequent | Pain between shoulder blades | |
3 | Yellow skin and eyes | ** | Upper abdominal pain | *** | Abdominal pain | *** | Frequent | Severe pain | *** |
4 | Pain | *** | Dark urine | * | Pain in upper abdomen | *** | Frequent | Mild pain | ** |
5 | Pain in upper abdomen | *** | Yellow skin and eyes | ** | Vomiting | *** | Frequent | Night pain | |
6 | Dark urine | * | Pain in upper abdomen | *** | Chills | * | Frequent | Abdominal discomfort | *** |
7 | Upper abdominal pain | *** | Intermittent abdominal pain | *** | Tenderness | *** | Frequent | Nausea | *** |
8 | Dry skin | Belching | Abdominal cramping from Gallstones | *** | Frequent | Side pain | * | ||
9 | Sleepiness | * | Discomfort in upper abdomen | *** | Yellow skin and eyes | ** | Frequent | Pain in upper-right abdomen | *** |
10 | Abdominal pain | *** | Abdominal pain | *** | Pain in upper-right abdomen | *** | Frequent | Flatulence | |
11 | Restless legs syndrome | Intermittent pain | *** | Diarrhea | * | Frequent | Indigestion | * | |
12 | Side pain | * | Swollen veins in the lower esophagus | Fever | ** | Frequent | Vomiting | *** | |
13 | Regurgitation | Fluid in the abdomen | Flank pain | * | Frequent | Abdominal cramping from Gallstones | *** | ||
