Table 6 Concentrations of polyunsaturated fatty acids in liver phospholipids of rat pups culled at day 2, according to the maternal diet (control or high-fat) and the gavage treatment during pregnancy [fish oil or control (water)].

From: Fish oil supplementation to rats fed high-fat diet during pregnancy prevents development of impaired insulin sensitivity in male adult offspring

 

Maternal control diet

Maternal high-fat diet

Control

Fish oil

Control

Fish oil

n

9

12

17

8

C16:0 (palmitic acid)

24.49 ± 1.06

24.41 ± 1.08

23.21 ± 0.58

24.13 ± 0.50

C16:1n-7 (palmitoleic acid)

1.32 ± 0.09

1.26 ± 0.07

0.70 ± 0.05††††

0.65 ± 0.05

C18:0 (stearic acid)

16.61 ± 1.04

16.19 ± 0.88

17.06 ± 0.61

15.53 ± 0.86

C18:1n-7 (cis-vaccenic acid)

1.87 ± 0.16

1.95 ± 0.11

1.61 ± 0.10

1.33 ± 0.08

C18:1n-9 (oleic acid)

9.67 ± 0.58

9.60 ± 0.48

10.47 ± 0.63

9.47 ± 1.00

C18:2n-6 (linoleic acid)

10.74 ± 0.40

10.45 ± 0.65

11.13 ± 0.35

11.39 ± 0.39

C18:3n-3 (α-linolenic acid)

0.23 ± 0.04

0.25 ± 0.03

0.19 ± 0.02

0.24 ± 0.02

C18:3n-6 (γ-linolenic acid)

0.44 ± 0.06

0.35 ± 0.03

0.36 ± 0.03

0.43 ± 0.048

C20:0 (arachidic acid)

0.62 ± 0.07

0.52 ± 0.06

0.60 ± 0.05

0.61 ± 0.06

C20:1n-9 (eicosenoic acid)

0.21 ± 0.03

0.28 ± 0.03

0.20 ± 0.01

0.26 ± 0.03

C20:2n-6 (eicosadienoic acid)

0.73 ± 0.05

0.72 ± 0.04

0.60 ± 0.03

0.61 ± 0.06

C20:3n-6 (dihomo-γ-linolenic acid)

0.75 ± 0.09

0.71 ± 0.06

0.85 ± 0.06

0.81 ± 0.10

C20:4n-6 (arachidonic acid)

17.57 ± 0.97

18.57 ± 1.25

18.84 ± 0.76

18.42 ± 0.60

C20:5n-3 (eicosapentaenoic acid)

0.65 ± 0.07

0.66 ± 0.05

0.51 ± 0.04

0.68 ± 0.05**

C22:4n-6 (adrenic acid)

4.06 ± 0.57

3.56 ± 0.46

3.37 ± 0.29

4.21 ± 0.23

C22:5n-6 (n-6 docosapentaenoic acid)

1.46 ± 0.29

1.39 ± 0.16

1.27 ± 0.11

0.19 ± 0.13

C22:5n-3 (n-3 docosapentaenoic acid)

4.71 ± 0.31

5.03 ± 0.28

4.77 ± 0.27

5.82 ± 0.53

C22:6n-3 (docosahexaenoic acid)

3.87 ± 0.33

4.18 ± 0.44

4.29 ± 0.25

4.23 ± 0.36

  1. Data are means ± standard errors. p < 0.05 and ††††p < 0.0001 for a maternal diet effect among the offspring of dams that received control gavage; **p < 0.01 for an effect of the gavage treatment between groups exposed to the same maternal diet.