Figure 5
From: Iron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis

Levels of isoprostane in Hfe +/+ and Hfe −/− mice. Levels of isoprostane in the heart of Hfe +/+ and Hfe −/− mice (n = 5 per group) at 1, 5, and 12 months of age were determined by 8-isoprostane kit. Data are presented as the means ± SEM. *p < 0.05 between Hfe −/− and Hfe +/+ mice assessed by the two-way ANOVA, followed by the Tukey’s post-hoc analysis.