Figure 2 | Scientific Reports

Figure 2

From: Metformin ameliorates the Phenotype Transition of Peritoneal Mesothelial Cells and Peritoneal Fibrosis via a modulation of Oxidative Stress

Figure 2

Effect of Metformin on TGF-β-induced Activation of Smad2/3 and MAPKinase Signaling. Metformin (1 µM) blocks TGF-β1-induced phosphorylation of Smad2/3 (A, 30 minutes), p38 and ERK1/2 MAPK (B, 3 hours). Representative western blots with quantitation bars (n = 6) are shown. *p < 0.05 vs. others, #p < 0.05 vs. TGF-β1.

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