Figure 7 | Scientific Reports

Figure 7

From: Ageing and latent CMV infection impact on maturation, differentiation and exhaustion profiles of T-cell receptor gammadelta T-cells

Figure 7

Effect of CMV on effector and effector memory differentiation stages. (a) Absolute numbers of early (CD27+CD28+), intermediate (CD27+CD28−) and late (CD27−CD28−) differentiated DN and (c) CD8+TCRγδ+ effector (CD45RO−CD197−, Temra) T-cells. (b) Absolute numbers of early, intermediate and late differentiated DN and (d) CD8+TCRγδ+ effector memory (CD45RO+CD197−, Temro) T-cells. Early (E), intermediate (I) and late (L) definitions are indicated in the upper right corners of the graphs. Scatter plots are indicated with the median. Significance was tested by a Kruskal-Wallis test, followed by a post-Dunn’s test for correction for multiple testing. Significance for the Dunn’s test is indicated in the plots: **p < 0.01; ***p < 0.001.

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