Figure 2

Ex-vivo stimulation assay. Levels of TNF-α and (b only) IL-6 in uncentrifuged PD effluent samples (4 h PET dwell) of 50 ml (a) initial cohort, n = 6) or 9 ml (b) independent validation cohort, n = 5) in volume, directly stimulated with LPS (0–100 ng/ml) at 37 °C for 4 or 24 h.