Figure 3
From: Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Interactions of atezolizumab and durvalumab with PD-L1. (a) Stereoview of the detailed PD-L1/atezolizumab Fab fragment interface. (b) Stereoview of the detailed PD-L1/durvalumab Fab fragment interface. In (a,b) the carbon atoms from PD-L1 and the antibody heavy and light chains are colored green, orange, and purple, respectively. Hydrogen bonds and salt bridges are indicated with dashed lines.
