Table 1 Characteristics of the sample of 1556 men and women in the MRC National Survey of Health and Development at age 60–64 with complete data.

From: Associations of statin use with motor performance and myalgia may be modified by 25-hydroxyvitamin D: findings from a British birth cohort

 

Men

Women

Men

Women

No Statin

Statin

No Statin

Statin

Total n in each group %

734

822

554

180

693

129

47.2

52.8

75.5

24.5

84.3

15.7

Outcomes

Intrusive body pain

32.6

43.6

30

40.6

41.3

55.8

Difficulty going up/down stairs

12.3

20.8

8.7

23.3

18.5

33.3

Difficulty gripping heavy objects

7.4

28.5

6.5

10

28.1

30.2

Chair Rise Speed (stands/min)

26.1

25.3

26.5

25

25.6

23.6

SD

(7.1)

(8.3)

(7.1)

(7.1)

(8.5)

(6.9)

Grip Strength max of 6 (kg)

45.3

24.7

45.4

44.9

24.8

24.3

SD

(11.9)

(7.9)

(12.2)

(11.1)

(8)

(7.9)

Inflammatory Markers & 25-hydroxyvitamin D

IL6 (log pg/ml)

0.7

0.7

0.7

0.9

0.6

0.9

SD

(0.7)

(0.7)

(0.7)

(0.7)

(0.7)

(0.6)

CRP (log mg/l)

0.8

0.8

0.7

0.8

0.8

0.9

SD

(0.8)

(0.9)

(0.8)

(0.9)

(0.9)

(0.8)

25-hydroxyvitamin D

 Normal >20 ng/l

30.4

33.5

32.3

24.4

34.3

28.7

 Insufficient 13–20 ng/l

34.2

33.6

32.7

38.9

32

41.9

 Deficient <13 ng/l

35.4

33

35

36.7

33.6

29.5

Covariates

BMI age 53 (kg/m2)

27.2

26.9

26.7

28.7

26.5

29.4

SD

(3.7)

(5)

(3.5)

(4)

(4.6)

(6.2)

Knee OA at 53 (Yes)

6.1

11.6

5.2

8.9

10.2

18.6

Education (by 26 years)

 None or Sub-GCE

35.4

38.1

32.1

45.6

36.2

48.1

 O-level

14.7

28.1

14.8

14.4

28

28.7

 A level/Degree or higher

49.9

33.8

53.1

40

35.8

23.3

SEC (age 53)

 I or II

57.1

40.1

58.1

53.9

41

35.7

 IIINM or IIIM

32.8

43.7

31.6

36.7

44.2

41.1

 IV or V

10.1

16.2

10.3

9.4

14.9

23.3

Cigarette Smoking

 Current

10.5

11.6

11

8.9

10.4

17.8

 Exsmoker

60.9

53.8

58.7

67.8

54.4

50.4

 Never

28.6

34.7

30.3

23.3

35.2

31.8

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