Table 1 Selected characteristics of subjects.

From: Mammographic density, blood telomere length and lipid peroxidation

 

All Women (n = 342)

Premenopausal (n = 173)

Postmenopausal (n = 169)

p valuea

Age (years)

50.4 (7.2)

44.8 (4.7)

56.0 (4.4)

<0.0001

Weight (kg)

68.5 (16.4)

66.9 (15.6)

70.1 (17.0)

0.07

BMI (kg/m2)

25.6 (5.9)

25.1 (5.7)

26.0 (6.1)

0.12

Waist (cm)

73.5 (13.9)

71.6 (13.2)

75.4 (14.3)

0.01

Parous (%)

72.5

70.5

74.6

0.40

Family History of breast cancer (%)b

22.5

23.7

21.3

0.60

Current Smoking (%)

12.6

14.5

10.7

0.29

Percent Mammographic Density (%)

40.2 (25.3)

43.7 (25.7)

36.6 (24.5)

0.01

Dense Area (cm2)

46.2 (32.6)

48.7 (31.4)

43.5 (33.6)

0.14

Non Dense Area (cm2- log)

4.19 (0.83)

4.08 (0.84)

4.30 (0.82)

0.02

Relative Telomere Length

1.03 (0.20)

1.10 (0.21)

0.97 (0.18)

<0.0001

Urinary MDA (umol/l – log)

7.96 (0.48)

7.85 (0.51)

8.07 (0.43)

<0.0001

  1. Continuous variables are presented as mean (SD) and categorical variables as percentage.
  2. ap value for comparison of pre and postmenopausal women. Two-sided two-sample t-test for continuous variables and Chi square test for categorical variables.
  3. bPercentage of subjects with at least one first degree family member with breast cancer.