Figure 4 | Scientific Reports

Figure 4

From: Sudan ebolavirus long recovered survivors produce GP-specific Abs that are of the IgG1 subclass and preferentially bind FcγRI

Figure 4

GP-specific reporters’ responses to SUDV survivors’ sera from longitudinal studies. 96 well culture plates were pre-coated with GP-Gulu antigen (5 µg/ml) and the activation assay was performed using sera samples from SUDV survivors collected during the period of 2001–2013. The sera samples were diluted 1:200 and 1:400 for all BW-FcγR cells. Supernatant was collected after 16 h and analyzed for mIL-2 by ELISA. n(2001/2013) = 7, n(2010) = 6. Two-tailed Mann Whitney test, *P value < 0.05; P value (2001–2010) = 0.0221, P value (2001–2013) = 0.0111.

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