Figure 4 | Scientific Reports

Figure 4

From: Transcriptome profiling of monocytes from XLA patients revealed the innate immune function dysregulation due to the BTK gene expression deficiency

Figure 4

The GO and KEGG pathway analysis of DE lncRNAs co-located genes in primary monocytes of XLA patients compared to healthy subjects. The significant GO biological process terms enriched for (a) DE annotated lncRNAs co-located genes, and (b) DE novel lincRNAs co-located genes. The number of DE lncRNAs co-located genes enriched in each GO terms is depicted above the bars in the figure. The significant KEGG pathway terms enriched for (c) DE annotated lncRNAs co-located genes, and (d) DE novel lincRNAs co-located genes. Each statistical significance value (adj.p-value) was negative log-10 base transformed. The numbers in the brackets indicate the total numbers of genes available in the KEGG database for each pathway terms. The number of identified DE lncRNAs co-located genes enriched in each KEGG pathways is depicted above the bars in the figure.

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