Figure 8

Effects of fibulin-3 knockdown and overexpression on tumor growth in a xenograft model. (A) Tumor growths in lentivirus transfection systems were observed continuously for 8 weeks. (B) The average volumes of the tumors formed in the fibulin-3 shRNA infected group were much lower than those formed by the negative control HOS-1. (C) The average volumes of the tumors formed by pLVX-fibulin-3 infected cells were much higher than those formed by the negative control HOS-29. *P < 0.05.