Table 1 Protein expression of fibulun-3 in human osteosarcoma tissues.
N | Fibulin-3 low (−/+) | Fibulin-3 high (++/+++) | X 2 | P | |||
|---|---|---|---|---|---|---|---|
n | % | n | % | ||||
Normal tissue | 60 | 56 | 93.3% | 4 | 6.7% | 108.28 | <0.01 |
Fibrous dysplasia | 70 | 58 | 82.9% | 12 | 17.1% | ||
Osteosarcoma | 160 | 43 | 26.9% | 117 | 73.1% | ||
Age (year) | 1.23 | >0.05 | |||||
<18 | 86 | 20 | 23.3 | 66 | 76.7 | ||
≥18 | 74 | 23 | 31.1 | 51 | 68.9 | ||
Sex | 0.70 | >0.05 | |||||
Male | 92 | 30 | 32.6 | 62 | 67.4 | ||
Female | 68 | 18 | 26.5 | 50 | 73.5 | ||
Pathological type | 0.34 | >0.05 | |||||
Fibroblastic osteosarcoma | 56 | 13 | 23.2% | 43 | 76.8% | ||
Osteoblastic osteosarcoma | 54 | 15 | 27.8% | 39 | 72.2% | ||
Chondroblastic osteosarcoma | 50 | 12 | 24% | 38 | 76% | ||
Enneking stage | 17.26 | <0.01 | |||||
Stage I | 61 | 29 | 47.5 | 32 | 52.5 | ||
Stage II | 56 | 13 | 23.2 | 43 | 76.8 | ||
Stage III | 43 | 5 | 11.6 | 38 | 88.4 | ||
Cell differentiation | 21.39 | <0.01 | |||||
High and intermediate | 82 | 35 | 42.7% | 47 | 57.3% | ||
Low | 78 | 8 | 10.3% | 70 | 89.7% | ||
Pulmonary metastases | 28.55 | <0.01 | |||||
Positive | 83 | 9 | 10.8 | 74 | 89.2 | ||
Negative | 77 | 38 | 49.4 | 39 | 50.6 | ||
Nodal status | 29.29 | <0.01 | |||||
Positive | 96 | 9 | 9.4% | 87 | 90.6% | ||
Negative | 64 | 30 | 46.9% | 34 | 53.1% | ||