Table 1 Protein expression of fibulun-3 in human osteosarcoma tissues.

From: RETRACTED ARTICLE: Fibulin-3 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition and activating the Wnt/β-catenin signaling pathway

 

N

Fibulin-3 low (−/+)

Fibulin-3 high (++/+++)

X 2

P

n

%

n

%

Normal tissue

60

56

93.3%

4

6.7%

108.28

<0.01

Fibrous dysplasia

70

58

82.9%

12

17.1%

  

Osteosarcoma

160

43

26.9%

117

73.1%

  

Age (year)

     

1.23

>0.05

<18

86

20

23.3

66

76.7

  

18

74

23

31.1

51

68.9

  

Sex

     

0.70

>0.05

Male

92

30

32.6

62

67.4

  

Female

68

18

26.5

50

73.5

  

Pathological type

     

0.34

>0.05

Fibroblastic osteosarcoma

56

13

23.2%

43

76.8%

  

Osteoblastic osteosarcoma

54

15

27.8%

39

72.2%

  

Chondroblastic osteosarcoma

50

12

24%

38

76%

  

Enneking stage

     

17.26

<0.01

Stage I

61

29

47.5

32

52.5

  

Stage II

56

13

23.2

43

76.8

  

Stage III

43

5

11.6

38

88.4

  

Cell differentiation

     

21.39

<0.01

High and intermediate

82

35

42.7%

47

57.3%

  

Low

78

8

10.3%

70

89.7%

  

Pulmonary metastases

     

28.55

<0.01

Positive

83

9

10.8

74

89.2

  

Negative

77

38

49.4

39

50.6

  

Nodal status

     

29.29

<0.01

Positive

96

9

9.4%

87

90.6%

  

Negative

64

30

46.9%

34

53.1%