Table 2 Frequency of SHP-2 genetic variations in preterm or full-term infants.

From: Functional variation of SHP-2 promoter is associated with preterm birth and delayed myelination and motor development in preterm infants

Variation (rs number)

Minor allele

Minor allele frequency

Variation (rs number)

Minor allele

Minor allele frequency

Preterm

Full-term

Preterm

Full-term

g.-317C > T (rs373537430)

T

0.007

0.000

IVS11 + 20 C > T (rs184743462)

T

0.007

0.009

g.-273G > A (rs58805176)

A

0.292

0.198

IVS11 − 75T > C

C

0.007

0.000

IVS1 + 21 C > G

G

0.028

0.009

IVS13 − 95C > T (rs3741983)

C

0.146

0.207

IVS2 + 143 G > A

A

0.000

0.009

P559S

T

0.007

0.000

IVS4 − 19C > T

T

0.007

0.000

IVS14 − 146G > A (rs4767860)

G

0.430

0.397

IVS10 − 63G > A (rs141247150)

A

0.007

0.000

1960T > C (rs17849094)

C

0.021

0.009

  1. Data was obtained from DNA samples from 72 preterm infants and 58 full-term infants. Nucleotide location numbers were assigned from the translational start site based on the SHP-2 mRNA sequence (GenBank accession number; NM_002834.3).
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