Figure 8

TIMP3 downregulates NRG1/ErbB4/SREBP2 signaling by the inhibition of ADAM17 activity, resulting in increased BA synthesis through enhancing Cyp7A1 expression.

TIMP3 downregulates NRG1/ErbB4/SREBP2 signaling by the inhibition of ADAM17 activity, resulting in increased BA synthesis through enhancing Cyp7A1 expression.