Figure 4 | Scientific Reports

Figure 4

From: Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells

Figure 4

The expanded DN T-cells express Vδ2 TCR. Flow cytometric panels showing the expression of Vδ1-TCR, Vδ2 TCR and CD56 marker on DN T-cells are shown (a). The frequency of Vδ2 within CD3 T-cells (b) was compared in HD (white bars), ZIKV (grey bars) and in DENV (hatched bars). The correlation between time after sympthoms onset (days) and the Vδ2 T cell frequency (c) during Zika infection is shown. The frequency of granzyme positive Vδ2 T cells (d) was compared in HD (white bars), ZIKV (grey bars) and in DENV (hatched bars). *p < 0.05.

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