Table 1 D10 values (The dose of radiation required to reduce the number of surviving colonies by 90%) in clonogenic survival assays of Fig. 4a and b.
Cell line | Expression Vector for | Silencing Vector for | D10 Value (Gy) |
|---|---|---|---|
EMT6/EF-Luc/shNC/EV | None (empty vector) | Scramble shRNA | 3.25 ± 0.08 |
EMT6/EF-Luc/shNC/UCHL1 | UCHL1 | Scramble shRNA | 5.54 ± 0.78* |
EMT6/EF-Luc/shHIF-1α/EV | None (empty vector) | HIF-1α shRNA | 3.49 ± 0.12 |
EMT6/EF-Luc/shHIF-1α/UCHL1 | UCHL1 | HIF-1α shRNA | 3.64 ± 0.17NS |
