Table 2 Comparison of concentrations of 16 cytokines between both study groups.

From: Cytokine-based Predictive Models to Estimate the Probability of Chronic Periodontitis: Development of Diagnostic Nomograms

Cytokine

Concentration in CGF (log2 pg/ml) Median (IQR)

P Value

Control group

Perio group

GMCSF

7.244 (1.214)

7.954 (1.485)

<0.001

IL1alpha

14.931 (0.889)

17.183 (1.665)

<0.001

IL1beta

11.500 (0.996)

14.132 (1.357)

<0.001

IL6

7.285 (1.956)

8.296 (2.002)

<0.001

IL12p40

3.120 (0.970)

4.173 (0.927)

<0.001

IL17A

3.006 (2.029)

4.867 (1.277)

<0.001

IL17F

2.046 (1.525)

3.373 (1.710)

<0.001

TNFalpha

2.862 (1.697)

4.554 (0.979)

<0.001

IFNgamma

2.417 (1.185)

3.363 (1.395)

0.001

IL2

3.424 (1.133)

3.973 (0.702)

<0.001

IL3

5.607 (1.071)

6.649 (1.880)

<0.001

IL4

2.745 (2.449)

3.713 (2.584)

<0.001

IL5

3.219 (1.301)

3.625 (0.836)

0.495

IL10

2.640 (1.577)

3.101 (2.080)

0.087

IL12p70

3.174 (3.053)

3.864 (1.976)

0.352

IL13

4.904 (2.881)

5.066 (3.514)

0.458

  1. IQR, interquartile range; CGF, crevicular gingival fluid. Concentration range for each biomarker analysed: GMCSF, 0.53–55,050 pg/ml; IFNgamma, 0.02–6,650 pg/ml; IL1alpha, 0.34–28,800 pg/ml; IL1beta, 0.09–23,150 pg/ml; IL2, 0.04–13,700 pg/ml; IL3, 0.19–26,500 pg/ml; IL4, 0.10–29,250 pg/ml; IL5, 0.04–17,800 pg/ml; IL6, 0.10–27,200 pg/ml; IL10, 0.04–10,050 pg/ml; IL12p40, 0.14–27,350 pg/ml; IL12p70, 0.26–18,050 pg/ml; IL13, 0.34–23,700 pg/ml; IL17A, 0.36–30,900 pg/ml; IL17F, 0.25–34,700 pg/ml; TNFalpha, 0.21–16,800 pg/ml.
Back to article page