Table 4 Apparent and bias-corrected measures of discrimination and classification of the six smoking-adjusted models based on cytokine levels.
Smoking-adjusted Model | ACC (%) | Sensitivity (%) | Specificity (%) | Positive Predictive Value (%) | Negative Predictive Value (%) | Diagnostic OR |
|---|---|---|---|---|---|---|
IL1alpha | 93.1 | 94.5 | 91.8 | 92.1 | 94.5 | 195.5 |
91.5 | 92.7 | 90.4 | 90.5 | 92.9 | 120.7 | |
Il1beta | 93.8 | 93.1 | 94.5 | 94.5 | 93.4 | 238.0 |
93.0 | 92.1 | 93.9 | 93.8 | 92.4 | 183.0 | |
IL17A | 89.1 | 89.0 | 89.1 | 89.0 | 89.2 | 67.0 |
88.0 | 88.2 | 87.9 | 87.8 | 88.4 | 55.0 | |
IL1alpha + IFNgamma | 95.2 | 93.1 | 97.2 | 97.1 | 93.5 | 489.5 |
93.7 | 91.7 | 95.7 | 95.6 | 92.3 | 249.3 | |
ILbeta + IL10 | 94.5 | 94.5 | 94.5 | 94.5 | 94.6 | 301.9 |
93.5 | 93.3 | 93.8 | 93.8 | 93.4 | 211.7 | |
IL17A + IFNgamma | 92.5 | 90.4 | 94.5 | 94.3 | 91.0 | 165.0 |
91.2 | 89.1 | 93.3 | 93.1 | 89.8 | 115.6 |
