Figure 3

Mean KPPS scores of patients with different genotypes of COMT rs6267 (A), COMT rs4680 (B), SCN9A rs6746030 (C), and OPRM1 rs1799971 (D). PD patients having different genotypes were further subgrouped into those without depression (light gray color) and those with depression (dark gray color). Data are expressed as mean + SEM. *Represents P < 0.05 and **represents P < 0.01.