Table 3 Hazard ratios (95% CI) of impaired cognition (MMSE ≤24 and ≤26) at 4th year follow-up by dietary acrylamide exposure among non-smoking Chinese elderly men and women.

From: Dietary acrylamide exposure was associated with mild cognition decline among non-smoking Chinese elderly men

 

Model 1 (crude)

P

Model 2 (full model)

P

HR (95% CI)

HR (95% CI)

4 th y MMSE ≤ 24 as cutoff

Men (n = 590)

1.015 (0.984, 1.047)

0.337

1.029 (0.996, 1.062)

0.085

Women (n = 1381)

0.995 (0.979, 1.012)

0.593

1.006 (0.989, 1.024)

0.498

4 th y MMSE ≤ 26 as cutoff

Men (n = 592)

1.226 (0.451, 3.330)

0.290

3.356 (1.064, 10.591)

0.039

Women (n = 1443)

0.596 (0.333, 1.069)

0.083

1.091 (0.531, 2.240)

0.831

  1. Data analysis was conducted by logistic regression model. Hazard rations (HR): Risk of MMSE ≤24 or ≤26 with an increase of 1 µg/d acrylamide intake. Adjusted variables included age (y), education, PASE total scores, dietary carbohydrate intake (% total energy), total AHA scores, baseline body weight, coffee (ml/d), tea drinking (ml/d), alcohol drinking (ml/d), medical history of diabetes (yes/no), stroke (yes/no), hypertension (yes/no), heart infarction (yes/no), any cancers (yes/no), total isoflavoens intake (mg/d), fruit and vegetables intakes (g/1000 kcal), fish consumption (g/1000 kcal). Total AHA scores were estimated based on the adherence index of American Heart Association on dietary and life style recommendations. MMSE: questionnaire for Mini-Mental State Exam.
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