Figure 1
From: Involvement of Monocyte Subsets in the Immunopathology of Giant Cell Arteritis
Total monocyte counts are elevated in newly diagnosed GCA and PMR patients. Absolute numbers of monocytes in freshly drawn whole blood obtained from healthy controls (HC, n = 20), newly-diagnosed patients with GCA (nGCA; n = 21), PMR (nPMR; n = 19) and in follow-up samples from patients in remission after 3 months of treatment (rGCA; n = 14, rPMR; n = 15). Data are expressed as Tukey box and whisker plots. The bottom and top of the box represent the first and third quartiles, and the band inside the box represents the second quartile (the median). The whiskers represent the 1.5 interquartile range (IQR) of the lower and the upper quartiles. The outlier is plotted as a dot. The Mann-Whitney U test was used to compare each patient group with HC. Paired samples (e.g. nGCA vs rGCA and nPMR vs rPMR) were compared with the Wilcoxon signed rank test. P-values of less than 0.05 (2-tailed) were considered statistically significant. P values are indicated in the graph.
