Table 2 Baseline characteristics of participants by incident erosive reflux disease.

Patients, No.

1367

10319

Age, median (IQR), y

51 (46–57)

50 (45–56)

0.621

Men, %

82.6

57.5

<0.001

BMI, median (IQR)

24 (23–26)

24 (22–26)

0.003

Change of BMI

0.25 ± 0.77

−0.13 ± 0.60

<0.001

Waist circumference, median (IQR), cm

87 (81–92)

83 (76–89)

<0.001

Change of waist circumference

0.60 ± 1.16

−0.10 ± 0.74

<0.001

 Systolic BP

115 (105–126)

114 (104–126)

0.574

 Diastolic BP

72 (65–80)

70 (63–78)

0.120

 Change of systolic BP

5.40 ± 7.39

2.65 ± 7.08

0.043

 Change of diastolic BP

3.40 ± 4.94

2.24 ± 4.80

<0.001

 Antihypertensive

26.6

20.4

<0.001

 Antiglycemic

7.3

5.3

0.007

 Aspirin

14.3

11.4

0.006

 Total cholesterol, mg/dL

190 (170–211)

191 (169–214)

0.300

 Change of total cholesterol

7.30 ± 10.30

−2.24 ± 10.25

<0.001

 Low-density lipoprotein

122 (104–141)

122 (104–143)

0.437

 Change of low-density lipoprotein

6.35 ± 7.37

−0.93 ± 7.44

<0.001

 High-density lipoprotein

53 (45–61)

55 (47–65)

<0.001

 Change of high-density lipoprotein

−0.05 ± 6.99

0.10 ± 6.52

<0.001

 Triglycerides, mg/dL

126 (90–175)

107 (77–151)

<0.001

 Change of triglycerides

11.60 ± 15.26

−4.09 ± 11.10

<0.001

 Glucose, mg/dL

91 (84–100)

89 (83–97)

<0.001

 Change of glucose

5.16 ± 6.11

−1.76 ± 6.67

<0.001

 HbA1c

5.4 (5.1–5.7)

5.4 (5.1–5.6)

<0.001

Diabetes mellitus, %

11.3

7.1

<0.001

Hypertension, %

27.7

21.5

<0.001

Dyslipidemia, %

20.9

17.6

0.003

 None

33.1

54.8

<0.001

 Former

37.6

28.9

 Current

29.3

16.3

Physical exercise, %

88.8

85.8

0.011