Figure 6

(A) Treatment schedule. Photomicrographs of brain (i) and histological brain sections at 5X (ii), 10X (iii) and 20X (iv) magnification obtained from brain dissected from glioma bearing mice treated with PBS (B), TMZ (C), and TMZ-LfNPs (D). (Necr. represents necrotic area with numerous penetrating tumor cells and blood vessels in the periphery of the tumor cell islets (arrows) as well as areas of haemorrhage (asterisks).