Table 4 The observed numbers and standardized incidence ratio of patients with active TB.

From: Active Tuberculosis Incidence and Characteristics in Patients Treated with Tumor Necrosis Factor Antagonists According to Latent Tuberculosis Infection

LTBI (+)

Patients

Follow up duration (y)

Patient-years

Observed

Expected*

SIR

95% CI

Male

134

3.19

427.46

3

0.38

7.89

1.28–23.04

Female

121

3.89

470.69

2

0.32

6.16

0.69–22.23

Age (years)

  20–29

14

2.83

39.62

1

0.03

  

  30–39

40

2.97

118.8

0

0.08

  

  40–49

70

4.14

289.8

1

0.19

  

  50–59

62

3.39

210.18

3

0.18

  

  60–69

46

3.81

175.26

0

0.21

  

  70–79

23

2.82

64.86

0

0.15

  

  ≥80

0

0

0

0

0

  

Overall

255

3.52

897.60

5

0.71

6.01

1.94–14.04

No LTBI

Patients

Follow up duration (y)

Patient-years

Observed

Expected*

SIR

95% CI

Male

222

2.98

661.56

3

0.59

5.10

1.02–14.89

Female

225

3.00

675.00

3

0.47

6.44

1.29–18.82

Age (years)

  20–29

112

2.68

300.16

1

0.25

  

  30–39

121

2.87

347.27

1

0.23

  

  40–49

93

3.24

301.32

1

0.20

  

  50–59

58

3.41

197.78

2

0.17

  

  60–69

41

2.8

114.8

0

0.14

  

  70–79

18

3.17

57.06

1

0.13

  

  ≥80

4

4.69

18.76

0

0.06

  

Overall

447

2.99

1336.53

6

1.06

5.14

1.88–11.18

  1. *To estimate ‘expected TB’ the sex and age specific TB patient notifications in 2011 were extrapolated from Korea centers for disease control and prevention. TB,tuberculosis; SIR, standardized incidence ratio; CI, confidence interval.