Figure 3

Raman spectral bands change with pregnancy and are delayed in the Cox-1 KO mouse compared to WT. Average Raman spectra from the 1265 cm⁻¹ peak (blue dashed line) and 1304 cm⁻¹ peak (blue dashed line) during different time points of pregnancy in WT (A) and Cox-1 KO (B) mice. (C) Mean ± SEM of the 1304 cm⁻¹ to 1265 cm⁻¹ peak ratio as a function of gestation in WT and Cox-1 KO mice (p < 0.05). (D) Modeled longitudinal trajectories of the 1304 cm⁻¹ to 1265 cm⁻¹ Raman peak ratio.