Figure 4

Raman spectra reveal delayed remodeling in the Cox-1 KO mouse at term. Mean ± SEM (A) and modeled longitudinal trajectories (B) of the 1657 cm⁻¹ to 1440 cm⁻¹ peak ratio. Mean ± SEM (C) and modeled longitudinal trajectory (D) of the non-negative least squares model collagen coefficient as a function of gestation in WT and Cox-1 KO mice.