Table 2 Inter-study reproducibility as evaluated by the absolute difference, coefficient of variation (COV) (expressed in %) and interclass correlation (ICC) between results from the first (CMR1) and second (CMR2) cardiac magnetic resonance exams, during isoflurane (IF) and pentobarbital (P) anesthesia.
Group IF | Group P | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
CMR1 | CMR2 | Absolute difference | COV | ICC [95%CI] (p) | CMR1 | CMR2 | Absolute difference | COV | ICC [95%CI] (p) | p† | |
LVM (µg) | 83.55 (7.22) | 87.26 (13.67) | 8.10 (8.58) | 8.64 (8.36) | 0.449 [−0.179–0.825] (0.074) | 81.10 (8.75) | 83.95 (11.35) | 9.68 (7.58) | 10.62 (7.42) | 0.279 [−0.437–0.794] (0.219) | 0.689 |
LVEDV (µL)§ | 53.92 (5.58) | 54.20 (7.14) | 3.96 (2.49) | 7.00 (4.28) | 0.737 [0.273–0.927] (0.003) | 62.54 (20.53) | 62.03 (8.28) | 14.07 (10.30) | 19.04 (12.62) | 0.380 [−0.341–0.832] (0.142) | 0.008 |
LVESV (µL) | 16.15 (4.03) | 15.84 (5.11) | 2.40 (1.97) | 12.97 (9.64) | 0.779 [0.361–0.939] (0.002) | 19.67 (12.58) | 18.46 (8.30) | 14.28 (9.35) | 50.26 (19.73) | −0.349 [−0.807–0.406] (0.824) | 0.001 |
LVEF (%) | 70.23 (5.56) | 71.12 (6.71) | 3.82 (2.55) | 5.36 (3.62) | 0.729 [0.256–0.924] (0.004) | 70.46 (10.26) | 70.07 (14.05) | 15.51 (11.99) | 19.43 (15.06) | −0.324 [−0.797–0.429] (0.805) | 0.008 |
RVEDV (µL)§ | 21.75 (5.95) | 20.61 (3.73) | 6.57 (3.04) | 26.21 (10.32) | −0.089 [−0.638–0.536] (0.601) | 36.64 (10.95) | 35.25 (8.00) | 11.56 (7.22) | 26.13 (13.49) | −0.040 [−0.661–0.638] (0.535) | 0.064 |
RVESV (µL)§ | 6.86 (2.81) | 5.37 (2.30) | 3.00 (2.64) | 37.09 (24.43) | −0.123 [−0.658–0.511] (0.640) | 15.20 (12.36) | 13.86 (5.03) | 9.55 (7.65) | 42.98 (15.82) | 0.157 [−0.535–0.741] (0.332) | 0.022 |
RVEF (%)§ | 68.68 (10.05) | 73.40 (11.81) | 12.54 (8.84) | 15.96 (9.74) | 0.052 [−0.546–0.630] (0.433) | 62.24 (19.22) | 60.11 (13.13) | 16.77 (11.63) | 25.26 (18.61) | 0.225 [−0.482–0.771] (0.267) | 0.393 |
Ecc base§ | −9.94 (2.80) | −10.33 (2.98) | 2.85 (2.48) | 45.13 (56.66) | 0.143 [−0.545–0.734] (0.346) | −13.05 (3.75) | −12.64 (1.81) | 2.67 (3.66) | 23.64 (32.53) | 0.539 [−0.151–0.885] (0.056) | 0.912 |
Ecc apex§ | −12.69 (2.85) | −11.86 (3.18) | 3.80 (3.67) | 55.12 (72.01) | −0.599 [−0.895–−0.103] (0.958) | −15.77 (2.35) | −14.70 (2.84) | 2.52 (2.71) | 18.25 (18.46) | 0.462 [−0.250–0.860] (0.093) | 0.505 |
Err base | 5.05 (1.96) | 7.10 (2.54) | 3.01 (2.90) | 32.62 (25.46) | −0.438 [−0.841–0.314] (0.833) | 4.88 (4.00) | 4.33 (2.14) | 2.12 (1.85) | 28.99 (19.22) | 0.330 [−0.391–0.813] (0.179) | 0.544 |
Err apex | 7.38 (1.99) | 4.91 (2.06) | 3.29 (2.21) | 40.35 (22.49) | 0.449 [−0.845–0.301] (0.890) | 6.47 (3.24) | 7.58 (2.87) | 4.56 (3.29) | 50.42 (35.89) | 0.447 [−0.268–0.855] (0.101) | 0.387 |
Ell§ | −10.65 (2.79) | −10.43 (2.24) | 2.93 (3.55) | 52.74 (90.08) | −0.758 [−0.948–−0.258] (0.994) | −14.08 (1.90) | −12.28 (2.13) | 2.48 (2.10) | 20.53 (15.04) | 0.234 [−0.475–0.775] (0.259) | 0.799 |