Table 1 Kinetic parameters of human TPST1 with substrate peptides.

From: Structural basis for the broad substrate specificity of the human tyrosylprotein sulfotransferase-1

Substrate

K m (µM)

k cat (min−1)

k cat/K m (min−1µM−1)

C4P5Y5 peptide

7.67 ± 1.7

4.90 × 10−2 ± 2.4 × 10−3

6.4 × 10−3

Gastrin peptide

6.52 × 102 ± 4.1 × 10

6.57 × 10−3 ± 4.5 × 10−4

1.0 × 10−5