Figure 2 | Scientific Reports

Figure 2

From: Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression

Figure 2

miR-125a-5p is selectively hyper-expressed in Treg cells isolated from PLN of patients with T1D. miR-125a-5p expression was measured by real time-PCR in Treg cells (A) and Tconv cells (B) purified from peripheral blood (PB) of non-diabetic control (CTR) donors (n = 8), pancreatic lymph nodes (PLN) of controls (n = 3) and from PB (n = 8) and PLN (n = 5) of patients with T1D. Expression values are reported as 2^-delta cycle threshold (2−dCT) values normalized using three different small RNAs (RNU6, RNU44, RNU48). *p < 0.05 student’s t test.

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