Table 1 Statistics of human kinase-specific substrates and their phosphorylation sites, derived from the Phospho.ELM database (version 9.0).
Kinase | Number of substrate sequences | Number of phosphorylation sites |
|---|---|---|
ATM (Ataxia telangiectasia mutated) | 29 | 58 |
CaM (Calcium/calmodulin-dependent protein kinase) | 37 | 62 |
CDKs (Cyclin-dependent kinases) | 120 | 274 |
CK1 (Casein kinase 1) | 20 | 56 |
CK2 (Casein kinase 2) | 108 | 255 |
GRK (G protein-coupled receptor kinase) | 18 | 73 |
GSK-3 (Glycogen synthase kinase 3) | 32 | 60 |
MAPKs (Mitogen-activated protein kinases) | 132 | 312 |
PKA (cAMP-dependent protein kinase) | 138 | 218 |
PKB (Protein kinase B) | 54 | 77 |
PKC (Protein kinase C) | 150 | 308 |
SRC (Src-family tyrosine kinase) | 63 | 100 |