Figure 5 | Scientific Reports

Figure 5

From: Intravenous infusion of human bone marrow mesenchymal stromal cells promotes functional recovery and neuroplasticity after ischemic stroke in mice

Figure 5

hBM-MSC promote neurogenesis in the subventricular zone and an increase in vessel density. (A) Representative micrograph shows the ROI selected for anatomical analyses. Quantification in subventricular zone (green box) indicates a significant increase of DCX in tMCAo hBM-MSC compared to tMCAo PBS mice (B,C). (D) CD31 analysis shows no difference in medial ROI (blue box), however an increase of vessel density is observed in perilesional cortex (red box) of tMCAo hBM-MSC compared to tMCAo PBS mice (E,F). Data are mean + SD, n = 6–10, unpaired t-test. *p < 0.05. Bar = 50 µm.

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