Table 1 List of GO terms enriched in expanded clones.

From: Dynamics and mechanisms of clonal expansion of HIV-1-infected cells in a humanized mouse model

GO_Id

GO_name

Odds ratio

P-value

Q-value

GO:0050900

leukocyte migration

0.522

0.008

0.059

GO:0016570

histone modification

0.568

0.009

0.059

GO:0051276

chromosome organization

0.664

0.009

0.059

GO:0016568

chromatin modification

0.635

0.009

0.059

GO:0016569

covalent chromatin modification

0.571

0.009

0.059

GO:0006325

chromatin organization

0.651

0.012

0.065

GO:0045321

leukocyte activation

0.643

0.019

0.079

GO:0046649

lymphocyte activation

0.627

0.018

0.079

GO:0001775

cell activation

0.702

0.040

0.148

  1. GO terms included in the Venn diagrams (Fig. 5D) were analyzed to determine statistical significance. P-value and Q-value was determined by using Fisher’s exact test or Storey Tibshirani method52, respectively. Odd ratio was calculated as SPEA/SAEP (SP; number of singleton IS present nearby genes related to a specific GO term, SA; number of singleton IS absent nearby those genes, EP; number of expanded IS present nearby those genes, and EA; number of expanded IS absent nearby those genes).