Figure 2 | Scientific Reports

Figure 2

From: Machine Learning-Assisted Network Inference Approach to Identify a New Class of Genes that Coordinate the Functionality of Cancer Networks

Figure 2

The properties of MALANI-Inferred Networks (MINs) across 9 cancer types. (a) Complete MINs reconstructed across cancer types via agglomeration of gene pairs selected by at least three different feature selection methods. Color codes denote different cancer types. (b) Shared gene pairs found across at least two cancer types indicated. (c) Top 10 enriched canonical pathways for genes residing in MIN for each cancer type. Heatmap plot based on negative of enrichment p-values at log2 scale. (d) Heatmap for genes found in MINs of at least 4 different cancer types. Heatmap plot based on the log2 scale of frequency, i.e. number of a given gene appearing in different gene pairs of an inferred network.

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