Figure 3
From: Soluble Epoxide Hydrolase Inhibition Protected against Angiotensin II-induced Adventitial Remodeling
TPPU administration regulated Calcineurin/NFATc3 signaling in adventitial remodeling mice. (A) Representative immunoblots and quantitation of CnA protein expression in aortas. (B) Measurement of CaN phosphatase activity in aortas. (C) Representative immunoblots and quantitation of p-NFATc3/NFATc3 expression in aortas. (D) Representative immunoblots and quantitation of NFATc3 nuclear translocation in aortas. Data were expressed as Mean ± SEM, n = 8 mice for each group. *p < 0.05 vs. Vehicle, #p < 0.05 vs. Ang II, **p < 0.05 vs. Vehicle (Cytoplasm), ##p < 0.05 vs. Ang II (Cytoplasm), &&p < 0.05 vs. Ang II + TPPU (Cytoplasm), $$p < 0.05 vs. Vehicle (Nucleus), ++p < 0.05 vs. Ang II (Nucleus).
