Figure 2 | Scientific Reports

Figure 2

From: Angulin proteins ILDR1 and ILDR2 regulate alternative pre-mRNA splicing through binding to splicing factors TRA2A, TRA2B, or SRSF1

Figure 2

ILDR1 translocates into the nuclei when TRA2A, TRA2B, or SRSF1 is present. (A) ILDR1-GFP localizes in the cytoplasm. (B–D) TRA2A-mCherry, TRA2B-mCherry, and SRSF1-mCherry localize in the nuclei. (E–G) When cotransfected, ILDR1-GFP moves into the nuclei, colocalizing with TRA2A-mCherry, TRA2B-mCherry, or SRSF1-mCherry. Expression vectors were transfected into COS-7 cells to express epitope-tagged proteins. Nuclei were stained with DAPI. Scale bar: 20 μm.

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