Figure 6
RAGE inhibition decreases the absolute number of leucocytes in the bronchoalveolar lavage (BAL). Total numbers of BAL leucocytes in uninjured, untreated mice (Sham group), acid-injured animals (HCl group) and acid-injured animals treated with sRAGE (HCl + recombinant sRAGE group) or with anti-RAGE monoclonal antibody (HCl + anti-RAGE mAb group) (n = 4–6 for each time-point). As no difference was observed between sham animals at all time points; the results from sham mice were mixed for analyses (left bar of the X-axis). Values are reported as means ± standard deviations. *P < 0.05 versus sham controls; #P < 0.05; ##P < 10−2 versus acid-injured animals.
