Table 1 Sociodemographic, clinical and microbiological characteristics across pregnant and non-pregnant cohort.

Age ^1,*

(n = 182)

(n = 310)

(Mean ± SD, Range)

33.6 ± 4.3 (21–45)

30.1 ± 7.6 (18.6–49.2)

18–25

5 (2.7%)

111 (36%)

26–35

122 (67%)

131 (42%)

36–49

55 (30.2%)

68 (22%)

Body mass index ¹

(n = 182)

(n = 307)

(Mean ± SD, Range)

23.1 ± 4.21 (17–43)

23.9 ± 5.2 (15–50)

Underweight (<18.50)

7 (3.8%)

18 (5.8%)

Normal weight (18.51–24.9)

140 (76.9%)

194 (62.6%)

Overweight (25.0–29.9)

26 (14.3%)

55 (17.7%)

Obese (>30)

9 (4.9%)

40 (12.9%)

Ethnicity ²

(n = 182)

(n = 306)

White

117 (64.3%)

200 (64.5%)

East Asian

26 (14.3%)

60 (19.4%)

South Asian

13 (7.1%)

12 (3.9%)

Black

4 (2.2%)

9 (2.9%)

Other/Mixed ethnicity

22 (12%)

25 (8%)

Smoking ^2,*

(n = 182)

(n = 310)

Yes

4 (2.2%)

39 (12.6%)

Alcohol

(n = 182)

(n = 310)

Yes

11 (6%)

no data

Unprotected sex ^2,*

(in the past 4 days)

(in the past 2 days)

Yes

47 (25.8%)

45 (14.5%)

Nugent category ^2,*

(n = 172)

(n = 307)

Not consistent with BV

111 (61%)

250 (80.6%)

Intermediate BV

36 (20%)

25 (8%)

Consistent with BV

25 (14%)

32 (10.3%)

CST ^2,*

(n = 182)

(n = 310)

I

56 (30.7%)

156 (50.3%)

II

12 (6.6%)

0 (0%)

III

30 (16.5%)

50 (16.1%)

IVA

0 (0%)

36 (11.6%)

IVC

26 (14.3%)

22 (7.1%)

IVD

42 (23.0%)

24 (7.7%)

V

16 (8.8%)

22 (7.1%)

Estimated bacterial load (total copies of 16 S rRNA gene)/swab ^1,*

(n = 181)

(n = 309)

(Mean ± SD, Range)

7.77 ± 0.93 (4.89–10.67)

6.83 ± 1.55 (3.50–10.31)

10⁴ or less

1 (0.5%)

47 (15.2%)

10⁵–10⁶

27 (15%)

97 (31.4%)

10⁷–10⁸

133 (73.5%)

146 (47.2%)

10⁹ or more

20 (11%)

19 (6.1%)

Presence of Mollicutes ^2,*

(n = 182)

(n = 310)

Yes

74 (40%)

217 (70%)

Presence of Ureaplasma ^2,*

42 (23%)

149 (48%)

U. parvum

39 (21.4%)

127 (41%)

U. urealyticum

3 (1.6%)

5 (1.6%)

Both

0 (0%)

1 (0.3%)