Table 3 Effect of tested compounds on ClC-Kb currents (expressed as the ratio of the current in presence of the compound over the current in the control).

RT93

10

0.07 ± 0.03*

Diflunisal

13

0.34 ± 0.05*

Loperamide

9

0.43 ± 0.08*

Chembridge 5939748

2

0.54 ± 0.07*

Chemdiv C798-0159

11

0.59 ± 0.05*

Chembridge 7917053

3

0.59 ± 0.09

Bupropion

9

0.62 ± 0.09*

Chembridge 6240156

3

0.66 ± 0.10

Chemdiv 3570-0493

3

0.67 ± 0.07*

Chemdiv 6228-1479

8

0.68 ± 0.08*

Chlorpheniramide maleate

5

0.75 ± 0.11

Mecloferamic acid

2

0.78 ± 0.07

Praziquante

2

0.78 ± 0.08

Chemdiv 6710-1801

5

0.78 ± 0.02*

Chemdiv 8015-5743

6

0.80 ± 0.21

Chemdiv 6228-1654

11

0.80 ± 0.22

Chemdiv 8016-1879

3

0.84 ± 0.05

Chembridge 7977288

2

0.84 ± 0.13

Chemdiv 2274-0341

7

0.85 ± 0.14

Chembridge 7917068

3

0.85 ± 0.25

Oxaprozin

6

0.87 ± 0.02*

Chemdiv 5596-0483

8

0.87 ± 0.09

Chemdiv 8018-8707

5

0.89 ± 0.02*

Chemdiv 4356-0640

8

0.89 ± 0.21

Chemdiv 4300-0449

5

0.90 ± 0.02*

Gefitinib

7

0.91 ± 0.04

Chembridge 14247123

3

0.92 ± 0.14

Chemdiv G856-6279

6

0.94 ± 0.10

Chemdiv 3570-0508

8

0.94 ± 0.04

Leflunomide

6

0.96 ± 0.02

Haloperidol

4

0.99 ± 0.06

Chemdiv 3931-2123

8

1.05 ± 0.05

Felodipine

4

1.06 ± 0.09

Baclofen

7

1.08 ± 0.08

Chemdiv 4356-0354

5

1.13 ± 0.04*

Chemdiv 4356-0657

6

1.19 ± 0.14

Chemdiv C200-7628

6

1.23 ± 0.09

Carprofen

4

1.29 ± 0.44

Chemdiv C200-7500

4

1.40 ± 0.27

Chlorphensin carbamate

3

1.73 ± 0.25