Figure 2
Effects of Hyp-GQDGLAGPK on corneal surface irregularities in the experimental dry eye mouse model. (A) Images of the eyes of the Hyp-GQDGLAGPK, cyclosporine, diquafosol, and sodium hyaluronate groups were photographed with a microscope at baseline; after DS 10d; and after treatment for 3, 5, 7, and 10 days. Scale bar = 1 mm. (B) The changes in the corneal irregularity scores was measured in the Hyp-GQDGLAGPK, cyclosporine, diquafosol and sodium hyaluronate groups. The quantitative data are presented as means ± SD (n = 13). The results are statistically significant by analysis of variance with the Tukey test at *p < 0.05 compared with baseline, # p < 0.05 compared with DS 10d and † p < 0.05 vs corresponding value in the normal saline group. Baseline = before desiccation stress; DS 10d = immediately after desiccation stress for 10 days; Tx 3d, Tx 5d, Tx 7d, and Tx 10d = 3, 5, 7 and 10 days after treatment with Hyp-GQDGLAGPK, cyclosporine, diquafosol, and sodium hyaluronate eye drops, respectively.
