Figure 5

Effect of Hyp-GQDGLAGPK on conjunctival goblet cell densities in the experimental dry eye mouse model. (A) The goblet cells of the conjunctiva were stained with PAS before desiccation stress, immediately after desiccation stress for 10 days, and 10 days after treatment with Hyp-GQDGLAGPK, cyclosporine, diquafosol, and sodium hyaluronate eye drops. Scale bar = 50 μm. (B) The goblet cell densities of each group are presented as means ± SD (n = 4~5 eyes). The results are statistically significant by analysis of variance with the Tukey test at *p < 0.05 compared with baseline, # p < 0.05 compared with DS 10d and † p < 0.05 vs corresponding value in the normal saline group.